The Insight Journal is an Open Access on-line publication covering the domain of medical image processing and visualization.

The unique characteristics of the Insight Journal include:

- Open-access to articles, data, code, and reviews
- Open peer-review that invites discussion between reviewers and authors
- Emphasis on reproducible science via automated code compilation and testing
- Support for continuous revision of articles, code, and reviews

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Impact of motion correction on the quantitative analysis of DCE-MR Images
Dynamic magnetic resonance imaging (DCE-MRI) carried out with contrast media such as Gd-chelate complex (Gd-DTPA) allows the non-invasive assessment of microcirculatory characteristics of malignant lesions. Quantitative estimation of lesion [...]

Collaborative Development of an open framework for medical simulation
This paper investigates an Open Framework for Medical Simulation (named SOFA for Simulation Open Framework Architecture), and proposes ideas for structuring and supporting its expansion. Lately, through a joint effort between the Sim Group at CIMIT and the [...]

ITK-based Registration of Large Images from Light Microscopy: A Biomedical Application
Inactivation of the retinoblastoma gene in mouse embryos results in morphological changes in the placenta, which has been shown to affect fetal survivability. The construction of a 3D virtual placenta aids in accurately quantifying structural changes [...]

N-Dimensional Path Optimization:  The Implementation of a Novel Algorithm in ITK
Using the path framework we previously added to ITK, we implemented a novel algorithm for n-dimensional path optimization, which we call the ND Swath (NDS). NDS uses dynamic programming to globally optimize the placement of a path within an image, subject to [...]

A DICOM-based Software Infrastructure for Data Archiving
In this paper , we propose an extension to the National Library of Medicine's Insight Segmentation and Registration Toolkit (ITK. with a companion image access and archival system that merges the image transfer capabilities of DICOM with DSpace [...]

Unsupervised Segmentation for Myofiber Counting in Immunofluorescent Microscopy Images
No opinion
The gold standard for measuring muscle regeneration in muscular dystrophy therapies is counting the number of dystrophin-positive muscle fibers on a cryostat muscle section immunostained for dystrophin. The standard process of manually counting a few thousand [...]

Cerebral Cortical Thickness Estimation using the TINA
  Open-Source Image Analysis Environment
This paper gives an overview of the use and development of the TINA open-source medical image analysis environment, with respect to the determination of human cerebral cortical thickness estimation from magnetic resonance images. The ultimate aim of TINA is [...]

A nonparametric, entropy-minimizing MRI tissue classification algorithm implementation using ITK
This paper focuses on the role of open-source software in the development of a novel magnetic resonance image (MRI) tissue classification algorithm. Specifically, we describe the of use existing classes in the Insight Segmentation and Registration Toolkit [...]

Integration of Fuzzy Mathematical Morphology and Fuzzy Spatial Relationships into ITK
No opinion
The aim of this paper is to present the integration of new filters computing fuzzy mathematical morphology and spatial relationships into ITK and to share our experience with the Open source community. Our implementation architecture follows the essential [...]

IGSTK: Development Process and Project Management Best Practices for an Open Source Software Toolkit for Image-Guided Surgery Applications
Open source technologies are increasing in popularity for software development. Many open source projects rely on skilled development teams whose members are distributed throughout the world. Often, agile development methods are employed by these teams, as [...]

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Publication of the Month
Image Kernel Convolution
by Tustison N., Gee J.

Issues Accepting Submissions
2017 January-December
281 days

Most Recent Reviews
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