The Insight Journal is an Open Access on-line publication covering the domain of medical image processing and visualization.

The unique characteristics of the Insight Journal include:

- Open-access to articles, data, code, and reviews
- Open peer-review that invites discussion between reviewers and authors
- Emphasis on reproducible science via automated code compilation and testing
- Support for continuous revision of articles, code, and reviews


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IGSTK: A State Machine Architecture for an Open Source Software Toolkit for Image-Guided Surgery Applications
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The Image-Guided Surgery Toolkit (IGSTK) is an Open Source software project being developed under NIH/NIBIB funding. The toolkit will provide a common platform for implementing image-guided surgery applications and for fostering research in the field. The [...]

Collaborative Development of an open framework for medical simulation
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This paper investigates an Open Framework for Medical Simulation (named SOFA for Simulation Open Framework Architecture), and proposes ideas for structuring and supporting its expansion. Lately, through a joint effort between the Sim Group at CIMIT and the [...]

ITK-based Registration of Large Images from Light Microscopy: A Biomedical Application
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Inactivation of the retinoblastoma gene in mouse embryos results in morphological changes in the placenta, which has been shown to affect fetal survivability. The construction of a 3D virtual placenta aids in accurately quantifying structural changes [...]

BioImage Suite: An integrated medical image analysis suite
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BioImage Suite is an integrated image analysis software suite developed at Yale. It uses a combination of C++ and Tcl in the same fashion as that pioneered by the Visualization Toolkit (VTK) and it leverages both VTK and the Insight Toolkit. It has [...]

N-Dimensional Path Optimization:  The Implementation of a Novel Algorithm in ITK
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Using the path framework we previously added to ITK, we implemented a novel algorithm for n-dimensional path optimization, which we call the ND Swath (NDS). NDS uses dynamic programming to globally optimize the placement of a path within an image, subject to [...]

Creation and Demonstration of a Framework for Handling Paths in ITK
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A hierarchy of path data types and basic path filters were added to ITK, providing a general framework for curves that map a scalar value to a point in n-dimensional space. The framework supports curves that are either continuous (parametric curves) or [...]

Camino: Diffusion MRI reconstruction and processing
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Camino is an open-source, object-oriented software package for processing diffusion MRI data. Camino implements a data processing pipeline, which allows for easy scripting and flexible integration with other software. This paper summarises the features of [...]

Clustering Based Cardiac Resynchronization Therapy Prediction using Open Source Toolkit PRTools
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We propose a novel framework at MICCAI 2005 to predict pacing sites in the left ventricle (LV) of a heart. This framework can be used to assist pacemaker implantation and programming in cardiac resynchronization therapy (CRT) that is a widely adopted therapy [...]

Impact of motion correction on the quantitative analysis of DCE-MR Images
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Dynamic magnetic resonance imaging (DCE-MRI) carried out with contrast media such as Gd-chelate complex (Gd-DTPA) allows the non-invasive assessment of microcirculatory characteristics of malignant lesions. Quantitative estimation of lesion [...]

Unsupervised Segmentation for Myofiber Counting in Immunofluorescent Microscopy Images
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The gold standard for measuring muscle regeneration in muscular dystrophy therapies is counting the number of dystrophin-positive muscle fibers on a cryostat muscle section immunostained for dystrophin. The standard process of manually counting a few thousand [...]

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Browse Journals
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Publication of the Month
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Boolean Operations on Surfaces in VTK Without External Libraries
by Quammen C., Weigle C., Taylor II R.M.

Issues Accepting Submissions
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2017 January-December
75 days
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Most Recent Reviews
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Worked very well and was easy to build
A Skull-Stripping Filter for ITK
by Jared Becksfort on 2017-09-19 16:03:36
Very interesting work
Isotropic and Steerable Wavelets in N...
by Le Zheng on 2017-06-02 11:07:04
Valuable contribution
A new implementation of...
by Dženan Zukić on 2016-07-28 15:40:50
Simple interface
A Skull-Stripping Filter for ITK
by Todd Jensen on 2016-05-30 08:00:15
A useful function, but with some build...
Walk In A Triangulation : Straight Walk
by Davis Vigneault on 2015-06-09 09:57:49
A meaningful contribution with...
Exact Geometrical Predicate: Point in...
by Davis Vigneault on 2015-06-09 11:10:14
Useful tool for kinetic analysis of PET...
InsightToolkit Kinetic Analysis...
by Matthew Mccormick on 2014-11-21 18:34:13
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