Diffusion tensor imaging (DTI) allows a quantitative study of the underlying geometry and architecture of white matter. We have developed a suite of open source tools for quantitative analysis of DTI suitable for use in clinical research studies. We have [...]

Diffusion tensor imaging has become an important research and clinical tool, owing to its unique ability to infer microstructural properties of living tissue. Increased use has led to a demand for statistical tools to analyze diffusion tensor data and [...]

A recent article by Van Hecke et al. [3] describes a framework for creating simulated diffusion-weighted images (DWI). The methodology allows for modeling intersubject variability, regional pathology, and noise and is quite useful for evaluation purposes. [...]

This paper describes the implementation of a resampling filter for Diffusion Tensor Images (DTI) in the Insight ToolKit (ITK). ITK already contains a filter for resampling scalar and vector images as well as several transformation and interpolation classes. [...]

White matter tractography enables studies of fiber bundle characteristics. Stochastic tractography facilitates these investigations by providing a measure of confidence regarding the inferred fiber bundles. This article presents a multithreaded ITK [...]

BioImage Suite is an NIH-supported medical image analysis software suite developed at Yale. It leverages both the Visualization Toolkit (VTK) and the Insight Toolkit (ITK) and it includes many additional algorithms for image analysis especially in the areas [...]