Recently, the scientific community has been proposing several automatic algorithms to biomedical image segmentation procedure, being an interesting and helpful approach to assist both technicians and radiologists in this time-consuming and subjective task. [...]

Non-negative Matrix Factorization (NMF) is a robust approach to learning spatially localized parts-based subspace patterns in applications such as document analysis, image interpretation, and gene expression analysis. NMF-based decomposition capabilities are [...]